BIO-RAD LABORATORIES CLINICAL DIV -- 170-9058 ACRYLAMIDE/BIS SOLUTIONS -- 6810-00F045789
===================== Product Identification ===================== Product ID:170-9058 ACRYLAMIDE/BIS SOLUTIONS MSDS Date:01/27/1995 FSC:6810 NIIN:00F045789 === Responsible Party === Company Name:BIO-RAD LABORATORIES CLINICAL DIV Address:2000 ALFRED NOBEL DR City:HERCULES State:CA ZIP:94547-5000 Country:US Info Phone Num:510-232-7000 Emergency Phone Num:510-232-7000 Preparer's Name:ROY WOOD CAGE:10987 === Contractor Identification === Company Name:BIO-RAD LABORATORIES Address:3300 REGATTA BLVD Box:City:RICHMOND State:CA ZIP:94804 Country:US Phone:415-232-7000 CAGE:10987 ============= Composition/Information on Ingredients ============= Ingred Name:ACRYLAMIDE (ANTICIPATED CARCINOGEN BY NTP) *95-4* CAS:79-06-1 RTECS #:AS3325000 Fraction by Wt: 0-40% OSHA PEL:0.3 MG/CUM (SKIN) ACGIH TLV:.03 MG/CUM SKIN (A2) EPA Rpt Qty:5000 LBS DOT Rpt Qty:5000 LBS Ingred Name:N,N'-METHYLENEBIS-ACRYLAMIDE *95-4* CAS:110-26-9 RTECS #:AS3678000 Fraction by Wt: 0.2% ===================== Hazards Identification ===================== LD50 LC50 Mixture:ORAL LD50(RAT): 295 MG/KG ACRYLAMIDE Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO Health Hazards Acute and Chronic:INHALATION: AIRBORNE ACRYLAMIDE IS READILY ABSORBED THROUGH THE LUNG, OVEREXPOSURE MAY BE NEUROTOXIC. EYES: CAN PRODUCE CONJUNCTIVAL IRRITATION. SKIN: READILY ABSORBED THROUGH UNBROKEN SKIN. INGESTION : NEUROTOXICITY CAN RESULT AFTER SWALLOWING SMALL AMOUNTS/MAY BE DELAYED OVER A PERIOD OF SEVERAL DAYS/WEEKS. Explanation of Carcinogenicity:NONE Effects of Overexposure:IRRITATION, PEELING/REDNESS OF SKIN, SWEATING OF HANDS & FEET, NUMBNESS, TINGLING & WEAKNESS IN EXTREMITIES, UNSTEADY GAIT, DECREASED REFLEXES, DROWSINESS, NERVOUS SYSTEM DISTURBANCES, LOSS OF VIBRATI ON & POSITION SENSES, NUMBNESS & TINGLING OF THE LIMBS. Medical Cond Aggravated by Exposure:PRE-EXISTING SKIN DISORDERS, EYE PROBLEMS, CENTRAL/PERIPHERAL NERVOUS SYSTEM CONDITIONS. ======================= First Aid Measures ======================= First Aid:EYES/SKIN: FLUSH W/LARGE AMOUNTS OF WATER FOR 15 MINS. INHALATION: REMOVE TO FRESH AIR AT ONCE. IF NOT BREATHING, GIVE CPR. INGESTION: IF CONSCIOUS, FOR LARGE SINGLE INGESTION, INDUCE VOMITING BY GIVI NG SYRUP OF IPECAC 30 ML FOLLOWED BY 2 GLASSES OF WATER/TOUCH BACK OF THROAT W/SPOON/FINGER. NEVER GIVE ANYTHING BY MOUTH IF UNCONSCIOUS/CONVULSING. OBTAIN MEDICAL ATTENTION IN ALL CASES. ===================== Fire Fighting Measures ===================== Extinguishing Media:NON-FLAMMABLE UNTIL ALL LIQUID HAS BOILED OFF. USE CO2, DRY CHEMICAL/WATER SPRAY FOR SURROUNDING FIRE. Fire Fighting Procedures:WEAR SELF CONTAINED BREATHING APPARATUS & FULL PROTECTIVE CLOTHING. DON'T USE HIGH-PRESSURE WATER STREAM. Unusual Fire/Explosion Hazard:MAY POLYMERIZE VIOLENTLY. AIRBORNE DUST CREATES AN EXPLOSION HAZARD. ================== Accidental Release Measures ================== Spill Release Procedures:WEAR PROTECTIVE EQUIPMENT & CLOTHING DURING CLEANUP PROCEDURES. COVER W/AN ABSORBENT, PICK UP & PLACE IN A SUITABLE CONTAINER FOR RECLAMATION/DISPOSAL. POLYMERIZE THE ACRYLAMIDE TO POLYACRYLAMIDE GEL FOR DISPOSAL. ====================== Handling and Storage ====================== Handling and Storage Precautions:KEEP IN TIGHTLY SEALED CONTAINER. STORE AT 39.2F IN A WELL-VENTILATED PLACE AWAY FROM INCOMPATIBLE MATERIALS. HANDLE IN A HOOD WHEN IN USE. Other Precautions:WEAR PROTECTIVE CLOTHING & APPROPRIATE RESPIRATORY PROTECTION. DON'T CUT, GRIND, WELD/DRILL ON/NEAR CONTAINER. PREVENT EYE & SCALP/SKIN CONTACT. ============= Exposure Controls/Personal Protection ============= Respiratory Protection:ORGANIC VAPOR CARTRIDGES PROVIDE PROTECTION UP TO 10% THE PEL. Ventilation:A CLOSED SYSTEM SHOULD BE EMPLOYED. LOCAL EXHAUST: TO PREVENT/CONTROL SKIN CONTACT, DUST GENERATION & VAPOR RELEASE. Protective Gloves:IMPERVIOUS RUBBER/PLASTIC Eye Protection:CHEMICAL SAFETY GOGGLES/FULL FACE SHIELD Other Protective Equipment:HEADCOVERING, EYE WASH FOUNTAIN, QUICK-DRENCH FACILITIES, RUBBER SHOES, LONG SLEEVED COVERALLS, LAB COAT. Work Hygienic Practices:REMOVE/LAUNDER CONTAMINATED CLOTHING & SHOES BEFORE REUSE. WASH HANDS THOROUGHLY AFTER USING & BEFORE EATING/SMOKING. Supplemental Safety and Health WEAR CLEAN CLOTHING DAILY. IT IS MANDATORY TO SHOWER & CHANGE CLOTHES BEFORE LEAVING WORK. DON'T TAKE CLOTHES/SHOES HOME. DON'T CARRY/CONSUME FOOD, GUM, TOBACCO PRODUCTS/DRINKS IN THE WORK AREA. PRODU CT IS SOLD AS 30ML/500ML BOTTLES OF 30/40% AQUEOUS SOLUTION OF ACRYLAMIDE & METHYLENEBISACRYLAMIDE/MIX. ================== Physical/Chemical Properties ================== Boiling Pt:B.P. Text:221F Vapor Pres:LIKE WATER Vapor Density:LIKE WATER Spec Gravity:1.04 Evaporation Rate & Reference:(BU ACETATE=1): AS WATER Solubility in Water:COMPLETE Appearance and Odor:CLEAR, COLORLESS & ODORLESS ================= Stability and Reactivity Data ================= Stability Indicator/Materials to Avoid:NO OXIDIZING & REDUCING AGENTS, BISULFIDES, PEROXIDES, ACIDS/BASES, VINYL INITIATORS, IRON, COPPER, ALUMINUM, BRASS,BRONZE. Stability Condition to Avoid:TEMPS >90F Hazardous Decomposition Products:BY THERMAL DECOMPOSITION: CO, CO2, AMMONIA, NITROGEN OXIDES Conditions to Avoid Polymerization:TEMPS >90F. ==================== Disposal Considerations ==================== Waste Disposal Methods:MAKE 100 ML OF A 10-20 W/V % ACRYLAMIDE SOLUTION IN WATER & PLACE IN A PLASTIC BAG LINING A 250-500 CC BEAKER. ADD 500 UL 10% AMMONIUM PERSULFATE & UL TEMED, STIR & ALLOW TO POLYMERIZE FOR 1 HR. DISPO SE OF IAW/LOCAL, STATE & FEDERAL REGULATIONS. Disclaimer (provided with this information by the compiling agencies): This information is formulated for use by elements of the Department of Defense. The United States of America in no manner whatsoever, expressly or implied, warrants this information to be accurate and disclaims all liability for its use. Any person utilizing this document should seek competent professional advice to verify and assume responsibility for the suitability of this information to their particular situation.