SIGMA CHEMICAL CO -- 5-BROMOURACIL, B9155 -- 6505-00N092671
===================== Product Identification ===================== Product ID:5-BROMOURACIL, B9155 MSDS Date:01/01/1999 FSC:6505 NIIN:00N092671 Status Code:A === Responsible Party === Company Name:SIGMA CHEMICAL CO Box:14508 City:ST LOUIS State:MO ZIP:63178 Country:US Info Phone Num:314-771-5765 Emergency Phone Num:314-771-5765 CAGE:21076 === Contractor Identification === Company Name:SIGMA CHEMICAL COMPANY Address:3050 SPRUCE ST Box:14508 City:ST LOUIS State:MO ZIP:63178 Country:US Phone:314-771-5765 CAGE:21076 ============= Composition/Information on Ingredients ============= Ingred Name:5-BROMOURACIL CAS:51-20-7 RTECS #:YQ9060000 Code:F = Wt:100. ===================== Hazards Identification ===================== Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO Health Hazards Acute and Chronic:ACUTE: HARMFUL IF SWALLOWED, INHALED, OR ABSORBED THROUGH SKIN. MAY CAUSE IRRITATION. CHRONIC: MAY ALTER GENTIC MATERIAL. TO THE BEST OF MANUFACTURER'S KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND TOXICOLOG ICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED. Effects of Overexposure:SEE HEALTH HAZARDS. ======================= First Aid Measures ======================= First Aid:IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED CLOTHING AND SHOES. IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHI NG GIVE ARTIFICIAL RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN. IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS. CALL A PHYSICIAN. WASH CONTAMINATED CLOTHING BEFORE REUSE. ===================== Fire Fighting Measures ===================== Extinguishing Media:WATER SPRAY. CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM. Fire Fighting Procedures:WEAR NIOSH APPRVD SCBA AND PROTECTIVE CLOTHING TO PREVENT CONTACT WITH SKIN AND EYES. Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS. ================== Accidental Release Measures ================== Spill Release Procedures:EVACUATE AREA. WEAR NIOSH APPRVD SCBA, RUBBER BOOTS AND HEAVY RUBBER GLOVES. WEAR DISPOSABLE COVERALLS AND DISCARD THEM AFTER USE. SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL. AVOID RAISING D UST. VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE. ====================== Handling and Storage ====================== Handling and Storage Precautions:DO NOT BREATHE DUST. DO NOT GET IN EYES, ON SKIN, ON CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE. MUTAGEN. KEEP TIGHTLY CLOSED. STORE IN A COOL DRY PLACE. Other Precautions:LABEL PRECAUTIONARY STATEMENTS: TOXIC. MAY CAUSE HERITABLE GENTIC DAMAGE. HARMFUL BY INHAL, IN CONT W/SKIN & IF SWALLOWED. IN CASE OF ACCIDENT/IF YOU FEEL UNWELL, SEEK MED ADVICE IMMED (SHOW LABEL WHE RE POSSIBLE). WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE PROTECTION. DO NOT BREATHE DUST . ============= Exposure Controls/Personal Protection ============= Respiratory Protection:WEAR APPROPRIATE NIOSH APPROVED RESPIRATOR. Ventilation:USE ONLY IN A CHEMICAL HOOD. Protective Gloves:CHEMICAL-RESISTANT GLOVES. Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES . Other Protective Equipment:ANSI APPROVED EYE WASH & DELUGE SHOWER . OTHER PROTECTIVE CLOTHING. Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING. Supplemental Safety and Health ================== Physical/Chemical Properties ================== Melt/Freeze Pt:>300.C, 572.F Appearance and Odor:WHITE POWDER. ================= Stability and Reactivity Data ================= Stability Indicator/Materials to Avoid:YES STRONG OXIDIZING AGENTS. Hazardous Decomposition Products:TOXIC FUMES OF: CARBON MONOXIDE, CARBON DIOXIDE, NITROGEN OXIDES, HYDROGEN BROMIDE GAS. =================== Toxicological Information =================== Toxicological Information:RTECS #:YQ9060000. URACIL, 5-BROMO-. TOXICITY DATA: IRP-RAT LD50:1700 MG/KG. PSEBBA 93,124,1956. IPR-MUS LD50:1400 MG/KG. PSEBAA 93,124,1956. TARGET ORGAN DATA: BEHAVIORAL (SOMNOLENCE). BEHAVIORAL (MU SCLE WEAKNESS). LUNGS, THORAX OR RESPIRATION (DYSPNAE). EFFECT ON NEWBORN (VIABILITY INDEX). ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RTECS) DATA IS PRESENTED HERE. SEE ACTUAL E NTRY IN RTECS FOR COMPLETE INFORMATION. ===================== Ecological Information ===================== Ecological:DATA NOT YET AVAILABLE. ==================== Disposal Considerations ==================== Waste Disposal Methods:DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS. =================== MSDS Transport Information =================== Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION. ===================== Regulatory Information ===================== Federal Regulatory Information:EUROPEAN INFO: TOXIC. R 46. MAY CAUSE HERITABLE GENETIC DAMAGE. R 20/21/22. HARMFUL BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED. S 45. IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE). S 36/37/39. WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE PROTECTON. S 22. DO NOT BREATHE DUST. REVIEWS, STANDARDS, AND REGULATIONS: OEL=MA K. EPA GENETOX PROGRAM 1988, NEGATIVE: S CEREVISIAE-HOMOZYGOSIS. EPA TSCA SECTION 8(B) CHEMICAL INVE NTORY. ======================= Other Information ======================= Disclaimer (provided with this information by the compiling agencies): This information is formulated for use by elements of the Department of Defense. The United States of America in no manner whatsoever, expressly or implied, warrants this information to be accurate and disclaims all liability for its use. Any person utilizing this document should seek competent professional advice to verify and assume responsibility for the suitability of this information to their particular situation.