QIAGEN INC -- BUFFER QC,QIAGEN RNA/DNA KIT, 14123,14142,14162 -- -
===================== Product Identification ===================== Product ID:BUFFER QC,QIAGEN RNA/DNA KIT, 14123,14142,14162 MSDS Date:09/22/1997 FSC:NIIN:Submitter:N EN Status Code:A === Responsible Party === Company Name:QIAGEN INC Address:28159 AVENUE STANFORD City:SANTA CLARITA State:CA ZIP:91355 Country:US Info Phone Num:800-362-7737 Emergency Phone Num:800-362-7737 CAGE:01QTQ === Contractor Identification === Company Name:QIAGEN INC Address:28159 AVENUE STANFORD Box:City:SANTA CLARITA State:CA ZIP:91355 Country:US Phone:800-362-7737 CAGE:01QTQ ============= Composition/Information on Ingredients ============= Ingred Name:AQUEOUS SOLUTION (CONTAINING INGREDIENTS 2 TO 4) Other REC Limits:N/K OSHA PEL:N/K OSHA STEL:N/K ACGIH TLV:N/K ACGIH STEL:N/K Ingred Name:SODIUM CHLORIDE %WT: 1000MM CAS:7647-14-5 RTECS #:VZ4725000 Fraction by Wt: ING NAME Other REC Limits:N/K OSHA PEL:N/K OSHA STEL:N/K ACGIH TLV:N/K ACGIH STEL:N/K Ingred Name:3-MORPHOLINOPROPANESULFONIC ACID; (3-MORPHOLINOPROPANSULFONIC ACID) CAS:1132-61-2 RTECS #:QE9104530 Code:F Fraction by Wt: 50% MM Other REC Limits:N/K OSHA PEL:N/K OSHA STEL:N/K ACGIH TLV:N/K ACGIH STEL:N/K Ingred Name:ISOPROPANOL CAS:67-63-0 RTECS #:NT8050000 = Wt:15. Other REC Limits:N/K OSHA PEL:980 MG/M3;400 PPM OSHA STEL:N/K ACGIH TLV:983 MG/M3;400 PPM ACGIH STEL:1230 MG/M3;500 PPM ===================== Hazards Identification ===================== Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO Health Hazards Acute and Chronic:ACUTE: INHALATION: MAY BE HARMFUL BY INHALATION. MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER RESPIRATORY TRACT. EYES: CAUSES SEVERE EYE IRRITATION. SKIN: CAUSES SKIN IRRITATION. MAY BE HARMFU L BY SKIN ABSORPTION. PROLONGED OR REPEATED EXPOSURE TO SKIN CAUSES DEFATTING AND DERMATITIS. INGESTION: MAY BE HARMFUL IF SWALLOWED. PROLONGED EXPOSURE: CAN CAUSE NAUSEA, HEADACHE, AND VOMITING NARCO TIC EFFECT. CAN CAUSE CENTRAL NERVOUS SYSTEM DEPRESSION. CHRONIC EFFECTS: TARGET ORGANS: NERVES, KIDNEYS. THE PRODUCT SHOULD BE HANDLED WITH THE NORMAL CAUTION ACCORDED CHEMICALS. ADDITIONAL HARMFUL P ROPERTIES CANNOT BE RULED OUT. Effects of Overexposure:SEE HEALTH HAZARDS. ======================= First Aid Measures ======================= First Aid:EYES: IMMEDIATELY FLUSH WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. ASSURE ADEQUATE FLUSHING OF THE EYES BY SEPARATING THE EYELIDS WITH FINGERS. SKIN: IMMEDIATELY WASH WITH SOAP AND COPIOU S AMOUNTS OF WATER. INHALATION: REMOVE TO FRESH AIR. IF NOT BREATHING, GIVE ARTIFICIAL RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN. INGESTION: WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONS CIOUS. CALL A PHYSICIAN. REMOVE AND WASH CONTAMINATED CLOTHING PROMPTLY. ===================== Fire Fighting Measures ===================== Flash Point:=27.5C, 81.5F Extinguishing Media:CARBON DIOXIDE, DRY CHEMICAL POWDER, OR APPROPRIATE FOAM. Fire Fighting Procedures:WEAR NIOSH APPROVED SCBA AND FULL PROTECTIVE EQUIPMENT . USE WATER SPRAY TO COOL FIRE-EXPOSED CONTAINERS. Unusual Fire/Explosion Hazard:VAPOR MAY TRAVEL CONSIDERABLE DISTANCE TO SOURCE OF IGNITION AND FLASH BACK. CONTAINER EXPLOSION MAY OCCUR UNDER FIRE CONDITIONS. ================== Accidental Release Measures ================== Spill Release Procedures:SHUT OFF ALL SOURCES OF IGNITION. EVACUATE AREA. WEAR NIOSH APPROVED SELF-CONTAINED BREATHING APPARATUS, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS, AND HEAVY RUBBER GLOVES. ABSORB ON SAND OR VERMICULITE A ND PLACE IN CLOSED CONTAINERS FOR DISPOSAL. USE NON-SPARKING TOOLS. VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE. ====================== Handling and Storage ====================== Handling and Storage Precautions:KEEP TIGHTLY CLOSED. STORE TIGHTLY CLOSED AT 20-25C. STORE IN COOL DRY PLACE. KEEP AWAY FROM HEAT, SPARKS, AND OPEN FLAME. Other Precautions:DO NOT GET IN EYES, ON SKIN, OR ON CLOTHING. DO NOT BREATHE VAPOR. SEVERE EYE IRRITANT. ============= Exposure Controls/Personal Protection ============= Respiratory Protection:NIOSH APPROVED RESPIRATOR. Ventilation:MECHANICAL EXHAUST REQUIRED. Protective Gloves:RUBBER GLOVES. Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES . Other Protective Equipment:ANSI APPROVED EMERGENCY EYEWASH AND DELUGE SHOWER . Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING. Supplemental Safety and Health WASTE DISPOSAL METHOD: UNLESS SPECIFIED DIFFERENTLY, NON-CONTAMINATED PACKAGING MAY BE TREATED LIKE HOUSEHOLD WASTE OR RECYCLED. DISPOSE OF IN ACCORDANCE WITH LOCAL, STATE, AND FEDERAL REGULATIONS (FP N). ================== Physical/Chemical Properties ================== Spec Gravity:1.013 G/CM3 @ 20C pH:7.0 @ 20C Solubility in Water:SOLUBLE @ 20C Appearance and Odor:COLORLESS LIQUID; CHARACTERISTIC ODOR. ================= Stability and Reactivity Data ================= OXIDIZING AGENTS, ACIDS, ACID ANHYDRIDES, HALOGENS, AND ALUMINUM. Hazardous Decomposition Products:TOXIC FUMES OF CARBON MONOXIDE AND CARBON DIOXIDE. =================== Toxicological Information =================== Toxicological Information:ORL-MAN LDLO: 5272 MG/KG AJCPAI 38, 144, 62. ORL-HMN LDLO: 3570 MG/KG 34ZIAG, 339, 69. UNR-MAN LDLO: 2770 MG/KG 85DCAI 2, 73, 70. ONLY SELECTED REGISTRY OF THE TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RT ECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR COMPLETE INFORMATION. ===================== Ecological Information ===================== Ecological:NOT APPLICABLE. ==================== Disposal Considerations ==================== Waste Disposal Methods:THERE ARE NO UNIFORM REGS FOR DISP OF CHEMS/RESIDUES. CHEM RESIDUES GEN COUNT AS SPECIAL WASTE. MFR RECOMMENDS THAY YOU CONT EITHER AUTHS IN CHARGE/APPRVD WASTE DISP COMPANIES WHICH WILL ADVISE YOU ON HOW TO DISPOSE OF SPECIAL WASTE. HANDLE CONTAM PACKAGING IN SAME WAY AS SUBSTANCE ITSELF. (SUP DAT) =================== MSDS Transport Information =================== Transport Information:NOT APPLICABLE. ===================== Regulatory Information ===================== SARA Title III Information:N/K --OTHER INFO: (980 MG/M3); STEL 800 PPM (1960 MG/M3) JANUARY 1993. OEL-TURKEY: TWA 200 PPM (500 MG/M3) JANUARY 1993. OEL-UNITED KINGDOM: TWA 400 PPM (980 MG/M3); STEL 500 PPM (1225 MG/M3); SKIN JA NUARY 1993. OEL-BULGARIA, COLOMBIA, JORDAN, KOREA, NEW ZEALAND, SINGAPORE, VIETNAM: CHECK ACGIH TLV. NIOSH REL TO ISOPROPYL ALCOHOL-AIR: 10H TWA 400 PPM; STEL 500 PPM NIOSH DHHS #92-100, 92. NOHS 1974 : HZD 40987; NIS 465; TNF 213605; NOS 252; TNE 3183554. NOES 1983: HZD 40987; NIS 449; TNF 183402; NOS 278; TNE 4665524; TFE 2058264. EPA GENETOX PROGRAM 1988, NEGATIVE: CELL TRANSFORM. (STATE REGS) Federal Regulatory Information:FLAM LIQ (USA DEFINITION), FLAM, R 10 (EUROPEAN DEFINITION) (ISOPROPANOL). ACGIH TLV-TWA 400 PPM; STEL 500 PPM 85INA8 5, 337, 86. IARC CANCER REVIEW: ANIMAL INADEQ EVIDENCE IMEMDT 15, 223, 77. IARC CA NCER REVIEW: HUMAN INADEQ EVIDENCE IMSUDL 7, 229, 87. IARC CANCER REVIEW: GROUP 3 IMSUDL 7, 229, 87. EPA FIFRA 1988 PEESTICIDE SUBJECT TO REGISTRATION/RE-REGISTRATION FEREAC 54, 7740, 89. MSHA STD-AIR : TWA 400 PPM (980 MG/M3) DTLVS 3, 141, 71. OSHA PEL: 8H TWA 400 PPM (980 MG/M3) FEREAC 54, 2923, 89 . OSHA PEL FINAL: 8H TWA 400 PPM (980 MG/M3); STEL 500 PPM (1225 MG/M3) FEREAC 54, 2923, 89. OEL-AUSTRALIA: TWA 400 PPM (OTHER INFO) State Regulatory Information:N/K --SARA REGS: SA7/SHE; N CRASSA-ANEUPLOIDY. EPA TSCA CHEMICAL INVENTORY, JUNE 1990 EPA TSCA SECTION 8(E) STATUS REPORT 8EHQ-1180-0371. EPA TSCA SECTION 8(E) STATUS REPORT 8EHQ-0985-0566. EPA TSCA T EST SUBMISSION (TSCATS) DATA BASE, JANUARY 1993. NIOSH ANALYTICAL METHODS: SEE ALCOHOLS 1, 1400. ======================= Other Information ======================= Disclaimer (provided with this information by the compiling agencies): This information is formulated for use by elements of the Department of Defense. The United States of America in no manner whatsoever, expressly or implied, warrants this information to be accurate and disclaims all liability for its use. Any person utilizing this document should seek competent professional advice to verify and assume responsibility for the suitability of this information to their particular situation.