SIGMA CHEMICAL CO -- HEXAMETHYLPHOSPHORAMIDE, H3380  -- 6810-00N055557
<pre>=====================  Product Identification  =====================

Product ID:HEXAMETHYLPHOSPHORAMIDE, H3380
MSDS Date:06/27/1994
FSC:6810
NIIN:00N055557
=== Responsible Party ===
Company Name:SIGMA CHEMICAL CO
Box:14503
City:ST LOUIS
State:MO
ZIP:63176
Country:US
Info Phone Num:314-771-5765
Emergency Phone Num:314-771-5765
CAGE:21076
=== Contractor Identification ===
Company Name:SIGMA CHEMICAL COMPANY
Address:3050 SPRUCE ST
Box:14508
City:ST LOUIS
State:MO
ZIP:63178
Country:US
Phone:314-771-5765
CAGE:21076

=============  Composition/Information on Ingredients  =============

Ingred Name:PHOSPHORIC TRIAMIDE, HEXAMETHYL-; (HEXAMETHYLPHOSPHORAMIDE)
     (SARA III)
CAS:680-31-9
RTECS #:TD0875000
OSHA PEL:N/K 
ACGIH TLV:N/K 

=====================  Hazards Identification  =====================

LD50 LC50 Mixture:LD50: (ORAL, RAT) 2650 MG/KG
Routes of Entry: Inhalation:YES  Skin:YES  Ingestion:YES
Reports of Carcinogenicity:NTP:YES    IARC:YES	  OSHA:NO
Health Hazards Acute and Chronic:ACUTE: MAY BE FATAL IF INHALED,
    SWALLOWED OR ABSORBED THROUGH SKIN. CAUSES EYE & SKIN IRRITATION.
    MATERIAL IS IRRITATING TO MUCOUS MEMBRANES & UPPER RESPIRATORY
    TRACT. CHRONIC: CARCINOGEN. DAMAGE TO T HE KIDNEYS & LUNGS. MAY
    ALTER GENETIC MATERIAL. TARGET ORGANS: KIDNEYS, LUNGS. TARGET ORGAN
    DATA: (EFTS OF OVEREXP)
Explanation of Carcinogenicity:PHOSPHORIC TRIAMIDE, HEXAMETHYL-: IARC
    MONOGRAPHS, SUPPLEMENT, VOL 7, PG 56, 1987:GROUP 2B. NTP 7TH ANNUAL
    (SUPDAT)
Effects of Overexposure:HLTH HAZ: PERIPHERAL NERVE & SENSATION (FLACCID
    PARALYSIS WITHOUT ANESTHESIA). SENSE ORGANS & SPECIAL SENSES
    (OLIFACTION TUMORS). BEHAVIORAL (ATAXIA). PATERNAL EFFECTS (TESTES,
    EPIDIDYMIS, SPERM DUCT) . TUMORIGENIC.
Medical Cond Aggravated by Exposure:NONE SPECIFIED BY MANUFACTURER.

=======================  First Aid Measures  =======================

First Aid:EYES/SKIN: IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN
    WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE
    REMOVING CONTAMINATED CLOTHING & SHOES. INHAL: REMOVE TO FRESH AIR.
    IF NOT BRE ATHING GIVE ARTIFICIAL RESPIRATION. IF BREATHING IS
    DIFFICULT, GIVE OXYGEN. INGEST: WASH OUT MOUTH WITH WATER PROVIDED
    PERSON IS CONSCIOUS. CALL MD. DISCARD CONTAMINATED CLOTHING &
    SHOES.

=====================  Fire Fighting Measures  =====================

Flash Point:222F,106C
Extinguishing Media:WATER SPRAY, CARBON DIOXIDE, DRY CHEMICAL POWDER OR
    APPROPRIATE FOAM.
Fire Fighting Procedures:USE NIOSH/MSHA APPROVED SCBA AND FULL
    PROTECTIVE EQUIPMENT .
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

==================  Accidental Release Measures  ==================

Spill Release Procedures:EVACUATE AREA. WEAR NIOSH/MSHA APPRVD SCBA,
    RUB BOOTS & HVY RUB GLOVES. WEAR DISP COVERALLS & DISCARD AFTER
    USE. COVER W/DRY LIME/SODA ASH, PICK UP, KEEP IN CLSD CNTNR & HOLD
    FOR WASTE DISP. VENT AREA  & WASH SPILL SITE AFTER MATL PICKUP
    ISCOMPLETE.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

======================	Handling and Storage  ======================

Handling and Storage Precautions:KEEP TIGHTLY CLOSED. STORE IN A COOL
    DRY PLACE.
Other Precautions:AVOID INHALATION. DO NOT GET IN EYES, ON SKIN, ON
    CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:WEAR APPROPRIATE NIOSH/MSHA APPROVED RESPIRATOR.
Ventilation:USE ONLY IN A CHEMICAL FUME HOOD.
Protective Gloves:CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPRVD SAFETY GOGGLES .
Other Protective Equipment:PROTECTIVE CLOTHING. ANSI APPRVD SAFETY
    SHOWER & EYE BATH .
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
HAZ DECOMP PROD: OXIDES &/OR PHOSPHINE. EXPLAN OF CARCIN: REPORT ON
    CARCINOGENS, 1994: ANTICIPATED TO BE CARCINOGEN.

==================  Physical/Chemical Properties  ==================

HCC:T6
Boiling Pt:B.P. Text:>446F,>230C
Melt/Freeze Pt:M.P/F.P Text:44.6F,7.0C
Vapor Pres:0.07 @ 25C
Vapor Density:6.18
Spec Gravity:1.030
Appearance and Odor:COLORLESS LIQUID.

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZING AGENTS, STRONG ACIDS.
Stability Condition to Avoid:NONE SPECIFIED BY MANUFACTURER.
Hazardous Decomposition Products:TOX FUMES OF CARBON MONOXIDE, CARBON
    DIOXIDE, NITROGEN OXIDES. THERMAL DECOMP MAY PRDCE TOX FUMES OF
    PHOSPHORUS (SUPDAT)

====================  Disposal Considerations  ====================

Waste Disposal Methods:DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE
    SOLVENT & BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
    AFTERBURNER & SCRUBBER. OBSERVE ALL FEDERAL, STATE & LOCAL
    ENVIRONMENTAL REGULATIONS.

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