BOEHRINGER MANNHEIM CORPORATION -- PROTEINASE K, 745723  -- 6505-00N092511
<pre>=====================  Product Identification  =====================

Product ID:PROTEINASE K, 745723
MSDS Date:12/09/1997
FSC:6505
NIIN:00N092511
Status Code:A
=== Responsible Party ===
Company Name:BOEHRINGER MANNHEIM CORPORATION
Address:9115 HAGUE RD
Box:50414
City:INDIANAPOLIS
State:IN
ZIP:46250-0100
Country:US
Info Phone Num:317-845-2000
Emergency Phone Num:317-845-2000
Resp. Party Other MSDS Num.:745723-1
Preparer's Name:MICHAEL A. FAZIO
CAGE:32239
=== Contractor Identification ===
Company Name:BOEHRINGER MANNHEIM CORPORATION
Address:9115 HAGUE RD
Box:50414
City:INDIANAPOLIS
State:IN
ZIP:46250-0100
Country:US
Phone:317-845-2000
CAGE:32239

=============  Composition/Information on Ingredients  =============

Ingred Name:BACILLUS SUBTILIS BPN; (PROTEOLYTIC ENZYME)
CAS:1395-21-7
RTECS #:CO9450000
= Wt:20.
Other REC Limits:N/K 
OSHA PEL:N/K 
OSHA STEL:N/K 
ACGIH TLV:0.00006 MG/M3
ACGIH STEL:C0.00006 MG/M3

=====================  Hazards Identification  =====================

Routes of Entry: Inhalation:NO	Skin:YES  Ingestion:NO
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:THE TOXICOLOGICAL PROPERTIES OF THIS
    PRODUCT HAVE NOT BEEN DETERMINED. A SMALL PERCENTAGE OF THE
    POPULATION WILL EXHIBIT ALLERGIC REACTIONS TO THE ENZYME. SYMPTOMS
    OF EXPOSURE MAY INCLUDE: FATIGUE, WE IGHT LOSS, COUGHING, AND
    SHORTNESS OF BREATH. THE ACGIH CEILING EXPOSURE LIMIT IS LISTED IN
    INGREDIENTS SECTION, IN MG/M3.
Effects of Overexposure:SEE HEALTH HAZARDS.
Medical Cond Aggravated by Exposure:NOT APPLICABLE.

=======================  First Aid Measures  =======================

First Aid:EYES: FLUSH CONTAMINATED EYES WITH LARGE VOLUMES OF WATER FOR
    AT LEAST 15 MINUTES. GET MEDICAL ATTENTION IF THE EYES REMAIN
    IRRITATED. SKIN: FLUSH CONTAMINATED AREAS WITH LARGE VOLUMES OF
    WATER FOR AT  LEAST 15 MINUTES, AS CONTAMINATED CLOTHING IS
    REMOVED. GET MEDICAL ATTENTION IF AREA REMAINS IRRITATED. DO NOT
    WEAR CONTAMINATED CLOTHING UNTIL AFTER IT HAS BEEN PROPERLY
    CLEANED. INGESTION: KEEP VIC TIM WARM AND CALM. GET IMMEDIATE
    MEDICAL ATTENTION. INHALATION: REMOVE VICTIM TO FRESH AIR. GIVE
    OXYGEN IF BREATHING BECOMES DIFFICULT. SHOULD BREATHING STOP, GIVE
    ARTIFICIAL RESPIRATION.

=====================  Fire Fighting Measures  =====================

Flash Point:>200.C, 392.F
Extinguishing Media:NO SPECIFIC INFORMATION IS KNOWN OF THE FLASH
    POINTS OR EXPLOSION LIMITS. USE MEDIA SPECIFIC FOR SITE CONDITIONS.
Fire Fighting Procedures:WEAR NIOSH APPROVED SCBA AND FULL PROTECTIVE
    EQUIPMENT . IF POSSIBLE, HAVE THIS PRODUCT REMOVED FROM THE FIRE
    SCENE.
Unusual Fire/Explosion Hazard:NOT APPLICABLE.

==================  Accidental Release Measures  ==================

Spill Release Procedures:VENTILATE THE AREA. INITIATE CLEANING UP THE
    SPILL USING THE EQUIPMENT AND MATERIALS AS NOTED IN THE 'CONTROL
    MEASURES' SECTION. IF THE PRODUCT IS DRY, MOP UP. IF THE MATERIAL
    IS IN SOLUTION, USE AN A BSORBENT MATERIAL TO PICK UP THE SPILLED
    SOLUTION. ONCE THE ABSORBENT IS SPENT, PLACE ALL CONTAMINATED
    DISPOSABLES INTO A SUITABLE CONTAINER, SEAL, LABEL, AND HOLD FOR
    DISPOSAL.

======================	Handling and Storage  ======================

Handling and Storage Precautions:SEE PACKAGE INSERT FOR STORAGE
    INFORMATION.
Other Precautions:NOT APPLICABLE.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:NONE REQUIRED IF VENTILATION IS ADEQUATE.
    DISPOSE OF IN ACCORDANCE WITH LOCAL, STATE, AND FEDERAL REGULATIONS
    .
Ventilation:PROVIDE ADEQUATE GENERAL EXHAUST VENTILATION.
Protective Gloves:RUBBER OR CHEMICAL-RESISTANT GLOVES SHOULD BE WORN.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EMERGENCY EYEWASH AND DELUGE
    SHOWER . A LAB COAT SHOULD BE WORN.
Work Hygienic Practices:DO NOT EAT, DRINK OR SMOKE WHILE WORKING WITH
    REAGENTS. UPON COMPLETION OF WORK ACTIVITIES INVOLVING THIS
    PRODUCT, WASH ANY EXPOSED BODY AREAS THOROUGHLY WITH SOAP AND
    WATER. (SUP DAT)
Supplemental Safety and Health
HYGIENE PRACTICES: WORK PRACTICES: GOOD LABORATORY TECHNIQUE SHOULD BE
    USED WHEN HANDLING THIS PRODUCT. DO NOT MOUTH PIPETTE! OBSERVE
    APPROPRIATE CHEMICAL HYGIENE. AVOID CONTACT WITH SKIN AND EYES.

==================  Physical/Chemical Properties  ==================

Solubility in Water:SHOULD BE FAIRLY SOLUBLE
Appearance and Odor:LYOPHILIZATE.

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
NOT APPLICABLE.
Stability Condition to Avoid:EXCESS HEAT, FLAME, AND PRESSURE.
Hazardous Decomposition Products:NOT APPLICABLE.

====================  Disposal Considerations  ====================

Waste Disposal Methods:DISPOSE OF IN ACCORDANCE WITH LOCAL, STATE, AND
    FEDERAL REGULATIONS.

=======================  Other Information  =======================

 Disclaimer (provided with this information by the compiling agencies):
 This information is formulated for use by elements of the Department
 of Defense.  The United States of America in no manner whatsoever,
 expressly or implied, warrants this information to be accurate and
 disclaims all liability for its use.  Any person utilizing this
 document should seek competent professional advice to verify and
 assume responsibility for the suitability of this information to their
 particular situation.